Non-invasive follicular thyroid neoplasm with papillary-like nuclear features; a single centre study
نویسندگان
چکیده
Introduction: Papillary carcinoma of the thyroid is commonest cancer in with an increasing incidence over past few decades. A subset papillary carcinomas was re-classified into “Non-invasive Follicular Thyroid Neoplasm papillary-like nuclear features” (NIFTP) late 2017, due to excellent prognosis they exhibit. Identification NIFTP important because surgical management and follow up similar follicular adenoma, thus reducing psychological burden patient, eliminating unnecessary exposure radiation economic society. This study intended assess prevalence inter-observer consistency identifying sample. Methods: retrospective, descriptive, cross-sectional included all specimens received at our department 2017. neoplasms a potential for reclassification were reassessed according WHO criteria by two investigators who blinded previous each other's diagnoses. Results: Out 256 received, 74/256 (28.90%) considered have be reclassified as which 34 cancers. Only 5/74 (6.75%) satisfied NIFTP. Three NIFTPs had been reported microcarcinoma other variant carcinoma. Inter-observer re-classifying 74 tumours 94.6%, 100% diagnosing Following re-classification, proportion cancers sample reduced 56/256 (21.87%) from 61/256 (23.82%). The 1.95% (5/256). Conclusions: comparable Asian population. current reports high recognizing among lesions, most likely strict adherence criteria.
منابع مشابه
[Non-invasive follicular thyroid neoplasm with papillary-like nuclear features].
Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was introduced to cover a group of noninvasive encapsulated follicular-patterned thyroid lesions with very low malignant behavior. This nomination may have a great impact on the incidence of thyroid malignancy and the practice for endocrine pathologists. To demonstrate the proportion of the thyroid follicular ...
متن کاملNoninvasive follicular thyroid neoplasm with papillary-like nuclear features: a single-institutional experience in Japan.
Noninvasive encapsulated follicular variant of papillary thyroid carcinoma (PTC) was reclassified as noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). To date, no studies on NIFTP have been reported in Japan. This study aimed to evaluate the clinical, cytological, and pathological findings of 54 cases of NIFTP from a single center in Japan, and compare them w...
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BACKGROUND The noninvasive Encapsulated follicular variant of papillary thyroid cancer (EFVPTC) has been reclassified as Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) without a significant risk for malignant behavior. However the evaluation remains a challenge for clinicians. We sought to determine whether programmed death-ligand 1 (PD-L1) expression may s...
متن کاملNoninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features: An Evidence-Based Nomenclature Change
A consensus panel recently used clinical evidence and pathologic parameters to rename noninvasive encapsulated follicular variant of papillary thyroid carcinoma to noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) to better reflect the indolent course of this tumor. NIFTP has stringent histopathologic diagnostic criteria established by the panel, including pap...
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ژورنال
عنوان ژورنال: Galle Medical Journal (Galle)
سال: 2022
ISSN: ['1391-7072']
DOI: https://doi.org/10.4038/gmj.v27i1.8143